臼井　達哉

Professional Career

経歴

2011/04/01 - 2013/03/31 : 日本学術振興会　特別研究員(DC1・農学)
2013/04/01 - 2013/10/31 : 日本学術振興会　特別研究員(PD・農学)
2013/11/01 - 2017/08/31 : 山口大学　共同獣医学部・獣医毒性学　助教
2015/04/01 - 2015/09/30 : スタンフォード大学　医学部　客員教員
2017/09/01 - 現在 : 東京農工大学　農学研究院　動物生命科学部門　特任講師

Academic Degrees

学位

2013/03　博士（獣医学）　北里大学

Research Interests

キーワード

オルガノイド 非アルコール性脂肪肝炎 獣医薬理学 獣医学 分子生物学 がん 三次元培養

Publications

論文

• Elbadawy M, Kato Y, Saito N, Hayashi K, Abugomaa A, Kobayashi M, Yoshida T, Shibutani M, Kaneda M, Yamawaki H, Mizutani T, Lim CK, Saijo M, Sasaki K, Usui T, Omatsu T. Establishment of Intestinal Organoid from Rousettus leschenaultii and the Susceptibility to Bat-Associated Viruses, SARS-CoV-2 and Pteropine Orthoreovirus. Int J Mol Sci. 2021 Oct 5;22(19):10763

• Endo T, Nakagomi Y, Kawaguchi E, Hayakawa ESH, Vu HN, Takemae H, Shinohara Y, Yang D, Usui T, Mizutani T, Nakao Y, Furuya T. Anti-malarial activity in a Chinese herbal supplement containing Inonotus obliquus and Panax notoginseng. Parasitol Int. 2022 Dec 18;87:102532. doi: 10.1016/j.parint.2021.102532. Epub ahead of print. PMID: 34933121.

• Elbadawy M, Kato Y, Saito N, Hayashi K, Abugomaa A, Kobayashi M, Yoshida T, Shibutani M, Kaneda M, Yamawaki H, Mizutani T, Lim C-K, Saijo M, Sasaki K, Usui T, Omatsu T. Establishment of Intestinal Organoid from Rousettus leschenaultii and the Susceptibility to Bat-associated Viruses, SARS-CoV-2 and Pteropine orthoreovirus. International Journal of Molecular Sciences, 22 (19) 10763, 2021
• Yamamoto H, Elbadawy M, Fujisaka K, Sato Y, Ohmori T, Shinohara Y, Hatano Y, Kobayashi D, Gomyo A, Sudo Y, Azakami D, Uchide T, Fukushima R, Morita S, Abugomaa A, Yamawaki H, Kaneda M, Usui T, Sasaki K. Evaluation of the Safety and Feasibility of Apheresis in Dogs: For Application in Metastatic Cancer Research. Animals 11 (10) :2770, 2021
• Elbadawy, M., Hayashi, K., Ayame, H., Ishihara, Y., Abugomaa, A., Shibutani, M., Hayashi, S. M., Hazama, S., Takenouchi, H., Nakajima, M., Tsunedomi, R., Suzuki, N., Nagano, H., Shinohara, Y., Kaneda, M., Yamawaki, H., Usui, T., Sasaki, K.: Anti-cancer activity of amorphous curcumin preparation in patient-derived colorectal cancer organoids. Biomed. Pharmacother. 142, 112043, 2021. https://doi.org/10.1016/j.biopha.2021.112043
• Elbadawy, M., Sato, Y., Mori, T., Goto, Y., Hayashi, K., Yamanaka, M., Azakami, D., Uchide, T., Fukushima, R., Yoshida, T., Shibutani, M., Kobayashi, M., Shinohara, Y., Abugomaa, A., Kaneda, M., Yamawaki, H., Usui, T., Sasaki, K.: Anti-tumor effect of trametinib in bladder cancer organoid and the underlying mechanism. Cancer Biol. Ther. 22(5-6), 357–371, 2021. https://doi.org/10.1080/15384047.2021.1919004
• Yamashita, R., Takahashi, Y., Takashima, K., Okano, H., Ojiro, R., Tang, Q., Kikuchi, S., Kobayashi, M., Ogawa, B., Jin, M., Kubota, R., Ikarashi, Y., Yoshida, T., Shibutani, M.: Induction of cellular senescence as a late effect and BDNF-TrkB signaling-mediated ameliorating effect on disruption of hippocampal neurogenesis after developmental exposure to lead acetate in rats. Toxicology 456: 152782, 2021.
• Abugomaa, A., Elbadawy, M., Yamanaka, M., Goto, Y., Hayashi, K., Mori, T., Uchide, T., Azakami, D., Fukushima, R., Yoshida, T., Shibutani, M., Yamashita, R., Kobayashi, M., Yamawaki, H., Shinohara, Y., Kaneda, M., Usui, T., Sasaki, K., Establishment of 2.5D organoid culture model using 3D bladder cancer organoid culture. Scientific Reports, 10(1), 9393, 2020.
• Elbadawy, M., Yamanaka, M., Goto, Y., Hayashi, K., Tsunedomi, R., Hazama, S., Nagano, H., Yoshida, T., Shibutani, M., Ichikawa, R., Nakahara, J., Omatsu, T., Mizutani, T., Katayama, Y., Shinohara, Y., Abugomaa, A., Kaneda, M., Yamawaki, H., Usui, T., Sasaki, K.: Efficacy of primary liver organoid culture from different stages of non-alcoholic steatohepatitis (NASH) mouse model. Biomaterials 237:119823, 2020
• Elbadawy, M., Usui, T., Mori, T., Tsunedomi, R., Hazama, S., Nabeta, R., Uchide, T., Fukushima, R., Yoshida, T., Shibutani, M., Tanaka, T., Masuda, S., Okada, R., Ichikawa, R., Omatsu, T., Mizutani, T., Katayama, Y., Noguchi, S., Iwai, S., Nakagawa, T., Shinohara, Y., Kaneda, M., Yamawaki, H., Sasaki, K. Establishment of a novel experimental model for muscle-invasive bladder cancer using a dog bladder cancer organoid culture.  Cancer Science (Cancer Sci.). 110(9):2806-2821, 2019.
• Nabeta R, Nakagawa Y, Chiba S, Xiantao H, Usui T, Suzuki K, Furuya T, Fukushima R, Uchide T. Pericardial Mesothelioma in a Dog: The Feasibility of Ultrasonography in Monitoring Tumor Progression. Front Vet Sci. 2019 Apr 18;6:121. doi: 10.3389/fvets.2019.00121. eCollection 2019.