田中　綾

Professional Career

経歴

2019年9月 - 現在 東京農工大学 グローバルイノベーション研究院 教授

Academic Degrees

学位

博士（獣医学）岐阜大学

Research Interests

キーワード

僧帽弁閉鎖不全症、体外循環

Publications

論文

• Hasegawa M, Sasaki M, Umemoto Y, Hayashi R, Hatanaka A, Hosoki M, Farag A, Hamabe L, Shimada K, Matsuura K, Yoshida T, Takahashi K, Tanaka R. Early detection of subclinical heart disease via nonlinear heart rate variability in a doxorubicin-induced cardiomyopathy experimental model in dogs. Front Vet Sci. 2025. (Provisional acceptance)

• Hirose M, Shimada K, Takeuchi A, Terai K, Yokoi A, Farag A, Hatanaka A, Hayashi R, Hosoki M, Azakami D, Nabeta R, Mitsui I, Hamabe L, Tanaka R. Pericardial sarcoma of uncertain origin in a young cat: A case report highlighting diagnostic challenges and thoracic drainage in palliative management. Animals. 15(23):3486. 2025.

• Hayashi R, Hasegawa M, Hatanaka A, Mandour AS, Hirose M, Shimada K, Hamabe L, Takahashi K, Tanaka R. Evaluation of changes in heart rate variability associated with puppy growth using phase-rectified signal averaging (PRSA) and non-Gaussianity index. Animals. 15(23):3449. 2025.

• Li Z, Farag A, Mandour AS, Xu T, Terai K, Shimada K, Hamabe L, Yokoi A, Yan S, Tanaka R. The role of phase angle in non-invasive fluid assessment in dogs with patent ductus arteriosus: A novel method in veterinary cardiology. Vet Sci. 12(10):1007. 2025.

• Mandour AS, Samir H, Farag A, Hamabe L, Matsuura K, Yoshida T, Watanabe G, Tanaka R. Concomitant Changes in Regional Myocardial Deformation and Intraventricular Pressure Gradients in Normal and Sedated Goats: Advanced Multimodal Echocardiographic Study. BMC Vet Res. 21(1):667. 2025.

• Li Z, Mandour AS, Farag A, Xu T, Terai K, Shimada K, Hamabe L, Yokoi A, Tanaka R. Phase angle as a non-invasive biomarker of fluid overload in canine right heart failure: A bioelectrical impedance approach. Animals. 15(19):2877. 2025.

• Ito N, Okamoto R, Shimada K, Azakami D, Yilmaz Z, Tanaka R, Hamabe L. Unroofed Coronary Sinus in a Dog: Diagnostic Utility of ECG-Gated Computed Tomography. Animals. 15(19): 2834. 2025.

• Yilmaz Z, Salci H, Levent P, Algan D, Varlik T, Topçu ME, Tanaka R, Hamabe L. Thromboelastographic Assessment of Coagulation Profiles in Dogs with Cardiac Tumors and Their Relationship to Cardiac Function. Animals. 15(18):2674. 2025.

• Farag A, Samir H, Koung Ngeun S, Kaneda M, Hendawy H, Takahashi K, Tanaka R. Comparative cardiomyocyte differentiation potential of rat adipose-derived mesenchymal stem cells from two anatomical sites: metabolomic profiling and pathway analysis. Front Cell Dev Biol. 13:1604605. 2025.

• Elhaieg A, Farag A, Koung Ngeun S, Kaneda M, Yokoi A, Mandour AS, Tanaka R Therapeutic Potential of Local and Systemic Adipose-Derived Mesenchymal Stem Cell Injections in a Rat Model of Experimental Periodontitis: Implications for Cardiac Function. Int J Mol Sci. 26(9). 2025.

• Helal May, Farag A, Elbadawy M, Usui T, Sasaki K, Tanaka R, Mandour AS. Early Detection of Lapatinib-Induced Cardiotoxicity in Dogs Using Intraventricular Pressure Gradients and Two-Dimensional Speckle-Tracking Echocardiography. Pakistan Veterinary Journal. 45(2):751-758. 2025.

• Zhao X, Tanaka R, Mandour AS, Shimada K, Hamabe L. Remote vital sensing in clinical veterinary medicine: A comprehensive review of recent advances, accomplishments, challenges, and future perspectives. Animals. 15(7):1033. 2025.

• Hirose M, Ma D, Shimada K, Yoshida T, Matsuura K, Kitpipatkun P, Hatanaka A, Zhao Y, Takahashi K, Tanaka R, Hamabe L. Effects of trans-mitral flow patterns and heart rate on intraventricular pressure gradients and E/E’ in the early stage of rat model of hypertensive cardiomyopathy. Frontiers in Veterinary Science. 12:1507817. 2025.

• Farag A, Hendawy H, Emam MH, Hasegawa M, Mandour AS, Tanaka R. Stem cell therapies in canine cardiology: comparative efficacy, emerging trends, and clinical integration. Biomolecules. 15(3), 371. 2025.

• Ueno S, Kawashima D, Matsuura K, Obara H, Tanaka R, Takei M. Real-time prediction of heparin concentration in blood extracorporeal circulation by relaxation time distribution (RTD) Bioelectrochemistry.163:108912. 2025.

• Hirose M, Hamabe L, Shimada K, Takeuchi A, Terai K, Yokoi A, Farag A, Hatanaka A, Hayashi R, Matsuura K, Tanaka R. Advanced imaging for congenital left ventricular diverticulum in a dog: the role of electrocardiosynchronous CT. Animals. 15(2):280. 2025.

• Hamabe L, Shimada K, Hirose M, Hasegawa M, Takeuchi A, Yoshida T, Azakami D, Mandour AS, Tanaka R. Assessment of myocardial function in Retrievers with dilated cardiomyopathy using 2D speckle tracking echocardiography: a pilot study. Frontiers in Veterinary Science. 11:1462437. 2024.

• Hirose M, Watanabe M, Takeuchi A, Yokoi A, Terai K, Matsuura K, Takahashi K, Tanaka R. Differences in the impact of left ventricular outflow tract obstruction on intraventricular pressure gradient in feline hypertrophic cardiomyopathy. Animals. 14(22):3320. 2024.

• Fukuzumi S, Mandour AS, Farag A, Yoshida T, Nishiura A, Yotsuida H, Yaginuma Y, Matsuura K, Tanaka R. Speckle tracking echocardiography for evaluation of myocardial functions before and after mitral valvuloplasty in dogs. Frontiers in Veterinary Science. 11:1463889. 2024.

• Farag A, Ngeun SK, Kaneda M, Aboubakr M, Elhaieg A, Hendawy H, Tanaka R. Exploring the potential effects of cryopreservation on the biological characteristics and cardiomyogenic differentiation of rat adipose-derived mesenchymal stem cells. International Journal of molecular Sciences. 25(18) 9908. 2024.

• Farag A, Ngeun SK, Kaneda M, Aboubakr M, Tanaka R. Optimizing Cardiomyocyte Differentiation: Comparative Analysis of Bone Marrow and Adipose-Derived Mesenchymal Stem Cells in Rats Using 5-Azacytidine and Low-Dose FGF and IGF Treatment. BIOMEDICINES. 12(8)1923. 2024.

• Hasegawa M, Sasaki M, Umemoto Y, Hayashi R, Hatanaka A, Hosoki M, Farag A, Matsuura K, Yoshida T, Shimada K, Hamabe L, Takahashi K, Tanaka R. Exploring sleep heart rate variability: linear, nonlinear, and circadian rhythm perspectives. FRONTIERS IN VETERINARY SCIENCE. 11:1386425. 2024.

• Shimada K, Hirose M, Hamabe L, Takai S, Jin D, Yilmaz Z, Kocaturk M, Tanaka R. Evaluation of alacepril administration in canine patent ductus arteriosus according to plasma chymase activity. ANIMALS. 14(7):1078. 2024.

• El-Husseiny HM, Mady EA, Hamabe L, Abugomaa A, Shimada K, Yoshida T, Tanaka T, Yokoi A, Elbadawy M, Tanaka R. Smart/stimuli-responsive Hydrogels: Cutting-Edge Platforms for Applications in Biomedicine and Tissue Engineering. Materials Today Bio. 13:100186. 2022.

• Ahmed S. Mandour, Haney Samir, Marwa A. El-Beltagy, Lina Hamabe, Hend A. Abdelmageed, Izumi Watanabe, Ahmed Elfadadny, Kazumi Shimada, Gamal El-Masry, Salim Al-Rejaie, Ryou Tanaka, Gen Watanabe. Monthly Dynamics of Plasma Elements, Hematology, Oxidative Stress Markers, and Hormonal Concentrations in Growing Male Shiba Goats (Capra hircus) Reared in Tokyo-Japan. Animals 2022, 12, 645

• Hendawy H, Yoshida T, Ma D, Takeuchi A, Ozai Y, Hamabe L, Tanaka R. Clinical and Diagnostic Approach of Male Pseudo Hermaphroditism with Os-Clitoris in French Bulldog: A Case Report. Veterinary Medicine and Science. DOI: 10.1002/vms3.764. 2022.

• Sasaki S, Ma D, Mandour AS, Ozai Y, Yoshida T, Matsuura K, Takeuchi A, Cheng CJ, El-Husseiny HM, Hendawy H, Shimada K, Hamabe L, Uemura A, Tanaka R. Evaluation of Changes in the Cardiac Function before and after Transcatheter Edge-to-Edge Mitral Valve Repair in Healthy Dogs: Conventional and Novel Echocardiography. Animals. 12(1):56. 2022.

• Shimada K, Hara S, Goya S, Mandour AS, Pitpitatkun P, Hamabe L, Uemura A, Takizawa J, Tanaka R. Butyric acid bacteria culture solution improves hyperglycemia in Alloxan-induced diabetes mellitus rats. Kafkas Univ Vet Fak Derg. 2021; 27(5):567-73.

• Hendawy H, Kaneda M, Metwally E, Shimada K, Tanaka T, Tanaka R. A Comparative Study of the Effect of Anatomical Site on Multiple Differentiation of Adipose-Derived Stem Cells in Rats. Cells. 10(9):2469. 2021.
• Yoshida T, Matsuura K, Goya S, Uemura A, Yilmaz Z, Tanaka R. Non-invasive Assessment of Pulmonary Artery Wave Reflection in Dogs with Suspected Pulmonary Hypertension. Frontiers in Veterinary Science. (Front Vet Sci.) 10.3389/fvets.2021.659194. 2021.
• Mandour AS, Mahmoud AE, Ali AO, Matsuura K, Samir H, Abdelmageed HA, Ma DF, Yoshida T, Hamabe L, Uemura A, Watanabe G, Tanaka R. Expression of cardiac copper chaperone encoding genes and their correlation with cardiac function parameters in goats. Veterinary Research Communications. (Vet Res Commun.) https://doi.org/10.1007/s11259-021-09811-5. 2021.
• Yoshida T, Mandour AS, Matsuura K, Shimada K, El-Husseiny HM, Hamabe L, Yilmaz Z, Uemura A, Tanaka R. Changes in the Pulmonary Artery Wave Reflection in Dogs with Experimentally-Induced Acute Pulmonary Embolism and the Effect of Vasodilator. Animals. 11(7):1977. 2021.
• Matsuura K, Shiraishi K, Mandour AS, Sato K, Shimada K, Goya S, Yoshida T, Kitpipatkun P, Hamabe L, Uemura A, Yilmaz Z, Ifuku M, Iso T, Takahashi K, Tanaka R. The Utility of Intraventricular Pressure Gradient for Early Detection of Chemotherapy-Induced Subclinical Cardiac Dysfunction in Dogs. Animals. 11(4):1122. 2021.
• Ahmed S. Mandour, Haney Samir, Tomohiko Yoshida, Katsuhiro Matsuura, Hend A. Abdelmageed 5,6, Mohamed Elbadawy , Salim Al-Rejaie, Hussein M. El-Husseiny, Ahmed Elfadadny, Danfu Ma , Ken Takahashi, Gen Watanabe 4 and Ryou Tanaka, Assessment of the Cardiac Functions Using Full Conventional Echocardiography with Tissue Doppler Imaging before and after Xylazine Sedation in Male Shiba Goats.  Animals 2020, 10, 12, 2320; doi:10.3390/ani10122320
• Ahmed S. Mandour, Asmaa O. Ali, Ahmed E. Mahmoud, Watanabe Izumi, Kazuaki Sasaki, Katsuhiro Matsuura, Kazumi Shimada, Ryou Tanaka, Gen Watanabe, The utility of electrocardiography and echocardiography in copper deficiency-induced cardiac damage in goats, Environmental Science and Pollution Research. , DOI: 10.1007/s11356-020-11014-5
• Ahmed S.Mandour, Haney Samir, Marwa A. El-Beltagy, Mohamed M. Abdel-Daim, Watanabe Izumi & Danfu Ma, Katsuhiro Matsuura, Ryou Tanaka, Gen Watanabe, Effect of supra-nutritional selenium-enriched probiotics on hematobiochemical, hormonal, and Doppler hemodynamic changes in male goats, Environmental Science and Pollution Research (2020) 27:19447–19460 https://doi.org/10.1007/s11356-020-08294-2