メニュー

池袋 一典

職位

教授

所属

工学研究院 生命機能科学部門
グローバルイノベーション研究院 ライフサイエンス分野・池袋チーム

Researcher ID

B-9957-2013

0000-0003-2838-0562

Email

ikebu(at)cc.tuat.ac.jp

URL

http://web.tuat.ac.jp/~tanpaku/

Professional Career

経歴

1993年4月 - 1996年3月- 東京大学 先端科学技術研究センター 助手
1996年4月 - 2001年3月- 東京大学 先端科学技術研究センター 講師
2001年4月- 現在 : 東京農工大学 工学部

Academic Degrees

学位

1992年 修士(工学)東京大学
1993年 博士(工学)東京大学

Research Interests

キーワード

核酸工学、バイオセンサ、アプタマー、進化分子工学、DNA/SNPセンサー、CpGメチル化検出、Aptamer、Evolutionary molecular、engineering、CpG methylation detection

Publications

論文

  • Miura D, Kimura H, Tsugawa W, Ikebukuro K, Sode K, Asano R, Rapid, convenient, and highly sensitive detection of human hemoglobin in serum using a high-affinity bivalent antibody-enzyme complex, Talanta, 234, 122638, doi: 10.1016/j.talanta.2021.122638., 2021.
  • Ariyanti D, Ikebukuro K, Sode K., Artificial complementary chromatic acclimation gene expression system in Escherichia coli, Microb Cell Fact, 20(1), 128, doi: 10.1186/s12934-021-01621-3., 2021.
  • Tsukakoshi K, Yamagishi Y, Kanazashi M, Nakama K, Oshikawa D, Savory N, Matsugami A, Hayashi F, Lee J, Saito T, Sode K, Khunathai K, Kuno H, Ikebukuro K, G-quadruplex-forming aptamer enhances the peroxidase activity of myoglobin against luminol, Nucleic Acids Res. 21, 49(11), 6069-6081. doi: 10.1093/nar/gkab388., 2021
  • Kimura H, Miura D, Tsugawa W, Ikebukuro K, Sode K, Asano R., Rapid and homogeneous electrochemical detection by fabricating a high affinity bispecific antibody-enzyme complex using two Catcher/Tag systems, Biosensors and Bioelectronics, 175, 112885. DOI: 10.1016/j.bios.2020.112885
  • Hatada M, Saito S, Yonehara S, Tsugawa W, Asano R, Ikebukuro K, Sode K., Development of glycated peptide enzyme sensor based flow injection analysis system for haemoglobin A1c monitoring using quasi-direct electron transfer type engineered fructosyl peptide oxidase, Biosensors and Bioelectronics, 177, 112984, 2021, DOI: 10.1016/j.bios.2021.112984.
  • Hiraka K, Tsugawa W, Asano R, Yokus MA, Ikebukuro K, Daniele MA, Sode K., Rational design of direct electron transfer type l-lactate dehydrogenase for the development of multiplexed biosensor, Biosensors and Bioelectronics, 176, 112933. DOI: 10.1016/j.bios.2020.112933.
  • Ito K, Okuda-Shimazaki J, Kojima K, Mori K, Tsugawa W, Asano R, Ikebukuro K, Sode K, Strategic design and improvement of the internal electron transfer of heme b domain-fused glucose dehydrogenase for use in direct electron transfer-type glucose sensors, Biosensors and Bioelectronics, 176, 112911. DOI: 10.1016/j.bios.2020.112911, 2021
  • Shono, C., Ariyanti, 2D., Abe, K., Sakai, Y., Sakamoto, I., Tsukakoshi, K., Sode, K., Ikebukuro, K., A green light-regulated T7 RNA polymerase 1 gene expression system 2 for cyanobacteria, Marine Biotechnology(Mar. Biotechnol.), DOI: 10.1007/s10126-020-09997-w
  • Lee, J., Tatsumi, A., Tsukakoshi, K., Wilson, E.D., Abe, K., Sode, K., Ikebukuro, K., Application of a Glucose Dehydrogenase-Fused with Zinc Finger Protein to Label DNA Aptamers for the Electrochemical Detection of VEGF, Sensors (Basel), 20(14), 3878, 2020
  • Fitriana, M., Loew, N., Witarto, A.B., Ikebukuro, K., Sode, K., Tsugawa, W., Employment of 1-Methoxy-5-Ethyl Phenazinium Ethyl Sulfate as a Stable Electron Mediator in Flavin Oxidoreductases-Based Sensors, Sensors (Basel), 20(10), 2825, 2020
  • Hiraka, K., Kojima, K., Tsugawa, W., Asano, R., Ikebukuro, K., Sode, K., Rational engineering of Aerococcus viridans l-lactate oxidase for the mediator modification to achieve quasi-direct electron transfer type lactate sensor. Biosensors and Bioelectronics (Biosens. Bioelectron.), 151, 111974, 2020.
  • Lee, I., Loew, N., Tsugawa, W., Ikebukuro, K., Sode, K. Development of a third-generation glucose sensor based on the open circuit potential for continuous glucose monitoring. Biosensors and Bioelectronics (Bios. Bioelectron. 124-125: 216-223, 2019
  • Tsukakoshi, K., Yoshida, W., Kobayashi, M., Kobayashi, N., Kim, J., Kaku, T., Iguchi, T., Nagasawa, K., Asano, R., Ikebukuro, K., Sode, K. Esterification of PQQ Enhances Blood-Brain Barrier Permeability and Inhibitory Activity against Amyloidogenic Protein Fibril Formation. ACS Chemical Neuroscience (ACS Chem Neurosci). doi: 10.1021/acschemneuro.8b00355, 9:12: 2898-2903
  • Hoshi, K., Yamazaki, T., Yoshikawa, C., Tsugawa, W., Ikebukuro, K., Sode, K. Synthesis of a hemin-containing copolymer as a novel immunostimulator that induces IFN-gamma production. International journal of Nanomedicine (Int. J Nanomedicine). 13:4461-4472, 2018

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